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- The safety of isotretinoin treatment in patients with bone fractures.
Accutane and broken bones -
Accutane can be used to treat a serious type of acne that cannot be obtained with the help of other treatments including antibiotics. However, Accutane can cause serious side effects. Before you start using Accutane, please discuss with your doctor how serious your acne is, the potential benefits of Accutane, and the possible side effects to determine whether Accutane is right for you.
Your doctor will ask you to read and sign one or more forms to show that you understand some serious risks of Accutane. Birth defects. If pregnant women take Accutane, it may cause birth defects deformed babies. It can also lead to miscarriage loss of the baby before birth , premature birth, or death of the baby. If you are pregnant or plan to take Accutane during pregnancy, please do not take Accutane. Do not get pregnant within 1 month after stopping taking Accutane.
In addition, if you become pregnant while taking Accutane, please stop taking it immediately and call your doctor. Mental problems and suicide. Some patients become depressed or have other serious mental problems when taking Accutane or shortly after stopping Accutane. Symptoms of these problems include sadness, "anxiety" or empty feelings, irritability, anger, loss of interest in social or physical activity, too much or too little sleep, changes in weight or appetite, decreased school or work performance, or Concentrate on trouble.
Some patients taking Accutane have thought of harming themselves or terminating their lives suicidal thoughts. Some people try to end their lives. Some people have already ended their lives. There are reports that some of them did not appear depressed. No one knows whether Accutane caused these behaviors, or even if the person did not take Accutane, it would not happen.
Do not get pregnant while taking Accutane or within 1 month of stopping Accutane. Even taking Accutane for a short period of time can cause serious birth defects in babies who take Accutane for pregnant women. If you are pregnant while taking Accutane, the risk of the baby deforming or dying is very high.
Taking Accutane will also increase the chance of miscarriage and premature delivery. Unless there is evidence that female patients have performed 2 negative pregnancy tests, female patients will not receive the first dose of Accutane. When your doctor decides to prescribe Accutane, the first test must be performed.
The second pregnancy test must be performed within the first 5 days of the menstrual period, that is, before starting treatment with Accutane, or as directed by the doctor.
Every month of treatment, the urine or serum pregnancy test must be negative. Unless there is evidence that a female pregnancy test is negative, female patients can no longer take Accutane.
The yellow self-adhesive Accutane qualification sticker on the prescription shows the pharmacist that your doctor is qualified for Accutane. When taking Accutane, effective birth control measures must be used. Before you start taking Accutane, you must use at least two effective birth control methods for at least 1 month, and you must stop taking Accutane for 1 month before taking Accutane.
You can discuss effective birth control methods with your doctor, or you can discuss birth control methods with another doctor or family planning expert for free. Your doctor can arrange this free visit, which will be paid by the manufacturer. You must use two separate effective methods of contraception, because any method, including birth control pills and sterilization methods, will fail.
You have two reasons not to use two effective birth control methods:. If you have not used two effective birth control methods for sexual activity at any time, are pregnant, or missed your menstrual period, please stop using Accutane and call your doctor immediately. If you are pregnant, plan to become pregnant, or get pregnant during Accutane treatment, do not take Accutane.
Accutane can cause serious birth defects. All women should read the "What are the important warnings for women taking Accutane" section. Do not take it unless you fully understand its possible risks and are willing to follow all the instructions in this "Guide to Medication. Tell your physician if you or your family members have any mental problems, asthma, liver disease, diabetes, heart disease, osteoporosis bone loss , weak bones, anorexia nervosa, or any other important health issues.
Tell your doctor about any food or drug allergies you have had in the past. These questions do not necessarily mean that you cannot take Accutane, but your doctor needs this information to discuss whether Accutane is right for you.
Don't get pregnant while taking Accutane. If a woman becomes pregnant while taking the Accutane, her baby can suffer severe brain and heart defects. If a pregnant person donates your blood from you, her child may be exposed to Accutane and may have a congenital defect.
High doses of vitamin A have many of the same side effects as Accutane. Taken together, they may increase your chance of side effects. Ask your doctor for advice on when plastic surgery can be performed. Avoid sunlight and ultraviolet rays as much as possible. The tanning machine uses ultraviolet light. Accutane can make your skin more sensitive to light. When you take Accutane, they may not work. If you are not sure which type to use, please consult your doctor or pharmacist.
If you plan to take other medicines or herbal products, please consult your doctor. This is especially important for patients using birth control pills and other hormone-type birth control pills, because if you take certain medicines or herbal products, the birth control pills may not work effectively. If you are currently taking Accutane orally or injecting corticosteroids or anticonvulsant seizures drugs, you should also talk to your doctor.
These drugs may weaken your bones. Do not take Accutane with antibiotics unless you talk to a doctor. For some antibiotics, you may have to stop taking Accutane until the end of antibiotic treatment. The use of two drugs together can increase the chance of increasing brain stress. Serious brain problems. Retinoic acid can increase stress in the brain. This can lead to permanent blindness or, in rare cases, death.
If you notice any of the following signs of increased cerebral pressure, stop taking Accutane and call your doctor immediately: severe headache, blurred vision, dizziness, nausea, or vomiting. In addition, some patients taking retinoic acid have seizures convulsions or stroke. Abdomen problems. Some symptoms may mean that your internal organs have been damaged. These organs include the liver, pancreas, intestine, and esophagus the connection between mouth and stomach.
If your organs are damaged, even if you stop taking Accutane, they may not get better. If you experience severe stomach, chest, or intestinal pain, difficulty swallowing or swallowing, new or worsening heartburn, diarrhea, rectal bleeding, yellowing of the skin or eyes, or dark urine, stop taking Accutane and call your doctor.
Bone and muscle problems. Retinoic acid may affect bones, muscles, and ligaments and cause joint or muscle pain. Tell your doctor if you plan to perform strenuous physical exercise during treatment with Accutane. Tell your doctor if you have pain, especially back pain or joint pain.
There are reports that some patients have acne growth retardation after taking retinoic acid as directed. There are also reports that after taking Accutane to treat acne as directed, bones will break, or fracture healing will decrease. No one knows whether taking Accutane to treat acne will affect your bones. If your bones are broken, please inform your service provider that you are taking Accutane.
Muscle weakness with or without pain may be a sign of severe muscle damage. If this happens, stop taking Accutane and call your doctor immediately. Hearing problems. Some people taking Accutane have hearing problems. Hearing loss may be permanent. If the hearing loss or tinnitus worsens, stop using Accutane and call your doctor. Vision problems. When taking Accutane, you may suddenly lose your ability to be invisible in the dark, so driving at night may be dangerous.
This condition usually disappears after you stop taking Accutane, but it may be permanent. Other serious eye reactions may occur. If you have any pain or persistent problems with your eyesight or dry eyes, stop taking Accutane, and call your doctor immediately.
Lipid problems. Many people who take retinoic acid have high levels of cholesterol and other fats in their blood. This may be a serious problem. Return to your doctor for a blood test to check your blood lipids and get the treatment you need. These problems usually disappear after Accutane treatment. Allergic reactions. In some people, retinoic acid may cause severe allergic reactions. If you have hives, swelling of the face or mouth, or difficulty breathing, stop taking Accutane immediately and get emergency care immediately.
If you have a fever, a rash, erythema, or bruises on your legs, stop taking Accutane and call your doctor. Signs of other possibly serious problems.
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One must remember that the therapy with isotretinoin can be complicated by acute rhabdomyolysis with a secondary impairment of long bone healing. Although several reports have suggested that isotretinoin use is associated with radiolucency of long bones and abnormal findings on bone scans, 3 recent. On the other hand, isotretinoin may induce acute rhabdomyolysis that have a negative effect on long bone healing due to muscle weakness. We suggest reducing the use of isotretinoin after bone injury or continuing the treatment at low dosing with a concomitant correction of vitamin. Accutane and Soriatane - known generically as isotretinoin and acitretin - are similar to vitamin A, which has been linked to broken bones when. Abstract Isotretinoin is widely applicable in dermatology, although it may develop severe side effects in the skeletal system. Even taking Accutane for a short period of time can cause serious birth defects in babies who take Accutane for pregnant women. For some antibiotics, you may have to stop taking Accutane until the end of antibiotic treatment.Bent u benieuwd hoe het apotheek. Bekijk dan de minimum. Hoewel bij het opstellen van de tekst uiterste zorgvuldigheid is betracht, is de KNMP niet aansprakelijk voor eventuele schade die zou kunnen voortvloeien uit enige onjuistheid in deze tekst.
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