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Accutane is a brand-name version of the drug isotretinoin. The brand is no longer available in the United States. However, the generic version of isotretinoin and other brand-name versions, such as Absorica, are still available. Isotretinoin is used to treat a type of severe acne called nodular acne.
Nodular acne causes red, swollen, tender lumps to form in the skin. If untreated, nodular acne can lead to permanent scarring.
While isotretinoin can help treat nodular acne, it can also cause many side effects. Some of these effects can be serious, especially if the drug is taken during pregnancy. These side effects may go away on their own. The more serious side effects of isotretinoin can have long-term or permanent effects.
However, apart from increased cholesterol and joint and muscle problems, these side effects are all quite rare. Isotretinoin can increase the levels of fats and cholesterol in your blood. During your treatment, your doctor may suggest regular blood tests to check your fat and cholesterol levels. This side effect, if you have it, typically goes away when you finish your treatment with isotretinoin. Learn more: What is metabolic syndrome? Tell your doctor if you plan to do hard physical activity during treatment with isotretinoin.
Isotretinoin can cause pain in your bones, joints, muscles, and ligaments. It can also stunt the growth of long bones in teens, which could have permanent effects. If you have any of the following symptoms, call your doctor right away:. If you break a bone, be sure to tell all of the healthcare providers that care for you that you take isotretinoin. If you have muscle weakness, with or without pain, stop taking isotretinoin and call your doctor right away.
Muscle weakness can be a sign of serious muscle damage and could be a permanent effect. Rarely, isotretinoin can cause increased pressure on the brain. This can lead to permanent loss of eyesight and, in rare cases, death.
Stop taking isotretinoin and call your doctor right away if you have any of these symptoms:. Although rare, a rash caused by isotretinoin can be serious. Stop using isotretinoin and call your doctor right away if you have any of the following symptoms:. Isotretinoin can damage your internal organs. These organs include your liver, pancreas, intestines, and esophagus the tube connecting your mouth and stomach. The damage may not get better even after you stop taking isotretinoin.
This side effect is rare. Still, stop taking isotretinoin and call your doctor right away if you have any of the following symptoms:. Isotretinoin can cause serious hearing problems in rare cases. Stop using isotretinoin and call your doctor right away if your hearing gets worse or if you have ringing in your ears. Any hearing loss may be permanent. Isotretinoin can cause vision problems such as blurry vision, double vision, and tunnel vision.
This drug can also reduce your ability to see in the dark. Vision problems may fix themselves after you stop taking the drug or the damage may be permanent. Isotretinoin can cause your eyes to produce more tears than normal. If you wear contact lenses, you may have trouble wearing them while taking isotretinoin. Like the other vision problems, this problem may go away after your stop treatment or it may be permanent.
All of these vision and eye problems are rare. Nevertheless, stop taking isotretinoin and call your doctor right away if you have problems with your vision, an increased amount of tears, or painful or constant eye dryness. Isotretinoin can cause serious allergic reactions in rare cases. Stop taking isotretinoin and call your doctor if you have a rash, red patches, or bruises on your legs or a fever. If you have any of the following symptoms, stop taking isotretinoin and call or go to the nearest emergency room:.
Isotretinoin may cause blood sugar problems, including diabetes. Call your doctor if you have any of the following symptoms:. Another rare, serious side effect is a decrease in blood cell levels. Low levels of red blood cells can cause problems such as anemia. Low levels of white blood cells raise your risk of infections. Rarely, isotretinoin can cause serious mental health problems. These include depression, psychosis losing touch with realityand suicidal thoughts or actions.
Taking isotretinoin during pregnancy carries an extremely high risk of severe birth defects. This is true if the drug is used in any amount and even for short periods of time. If you become pregnant during treatment with isotretinoin, stop taking the drug right away. A gynecologist can then give you further evaluation and counseling. Because of the risks it carries for pregnancies, isotretinoin can be prescribed only under a special restricted distribution program called iPLEDGE.
This program is approved by the Food and Drug Administration. Both males and females who take isotretinoin need to discuss this program with their doctor. Doctors who prescribe isotretinoin and pharmacies that dispense isotretinoin must be registered and activated with the iPLEDGE Program. The second pregnancy test must be done in a lab specified by your doctor. The program also requires females to choose and agree to use two forms of effective birth control at the same time.
This precaution goes along with the third requirement. That is, you must agree not to become pregnant while using isotretinoin and for one month before or after treatment. At least one of the birth control methods must be a primary form of birth control. Examples of these forms are tubal ligation having your tubes tiedan IUD, and hormonal birth control.
Another approach is for your partner to have a vasectomy. The only exceptions to this requirement are if you have chosen not to have intercourse with a male abstinence or have had a hysterectomy surgery to remove your uterus.
As you can see, there are many risks linked with isotretinoin use. If you have more questions about these side effects, talk with your doctor. Questions you may ask include:. Your doctor can help you decide if isotretinoin is the right drug for you. They can also help you manage any side effects you have. Isotretinoin belongs to a class of drugs called retinoids. Less oil on your skin gives the acne-causing bacteria less to feed on.
With fewer clogged pores, bacteria have fewer places to grow. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. Accutane was the brand name of a drug for severe acne treatment called isotretinoin. Understanding the risks and knowing the signs of common STDs is crucial for men who are sexually active. Learn how to spot the main symptoms.
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There are treatments and skin care habits that can help. What can you do about acne scars? While the AAD suggest things like surgery and laser resurfacing, you might also find relief through less invasive…. While it may be tempting to pop your own pimple, experts recommend that you resist the urge. How Well Do You Sleep? Skin Care. More common side effects Serious side effects Pregnancy warning Takeaway Introduction Accutane is a brand-name version of the drug isotretinoin.
❾-50%}Can you take cold medicine on accutane.Common questions about isotretinoin capsules
The more serious side effects of isotretinoin can have long-term or permanent effects. However, apart from increased cholesterol and joint and muscle problems, these side effects are all quite rare. Isotretinoin can increase the levels of fats and cholesterol in your blood.
During your treatment, your doctor may suggest regular blood tests to check your fat and cholesterol levels. This side effect, if you have it, typically goes away when you finish your treatment with isotretinoin. Learn more: What is metabolic syndrome? Tell your doctor if you plan to do hard physical activity during treatment with isotretinoin.
Isotretinoin can cause pain in your bones, joints, muscles, and ligaments. It can also stunt the growth of long bones in teens, which could have permanent effects. If you have any of the following symptoms, call your doctor right away:. If you break a bone, be sure to tell all of the healthcare providers that care for you that you take isotretinoin.
If you have muscle weakness, with or without pain, stop taking isotretinoin and call your doctor right away. Muscle weakness can be a sign of serious muscle damage and could be a permanent effect. Rarely, isotretinoin can cause increased pressure on the brain. This can lead to permanent loss of eyesight and, in rare cases, death. Stop taking isotretinoin and call your doctor right away if you have any of these symptoms:. Although rare, a rash caused by isotretinoin can be serious.
Stop using isotretinoin and call your doctor right away if you have any of the following symptoms:. Isotretinoin can damage your internal organs. These organs include your liver, pancreas, intestines, and esophagus the tube connecting your mouth and stomach. The damage may not get better even after you stop taking isotretinoin. This side effect is rare. Still, stop taking isotretinoin and call your doctor right away if you have any of the following symptoms:.
Isotretinoin can cause serious hearing problems in rare cases. Stop using isotretinoin and call your doctor right away if your hearing gets worse or if you have ringing in your ears. Any hearing loss may be permanent. Isotretinoin can cause vision problems such as blurry vision, double vision, and tunnel vision.
This drug can also reduce your ability to see in the dark. Vision problems may fix themselves after you stop taking the drug or the damage may be permanent. Isotretinoin can cause your eyes to produce more tears than normal. If you wear contact lenses, you may have trouble wearing them while taking isotretinoin.
Like the other vision problems, this problem may go away after your stop treatment or it may be permanent. All of these vision and eye problems are rare. Nevertheless, stop taking isotretinoin and call your doctor right away if you have problems with your vision, an increased amount of tears, or painful or constant eye dryness.
Isotretinoin can cause serious allergic reactions in rare cases. Stop taking isotretinoin and call your doctor if you have a rash, red patches, or bruises on your legs or a fever. If you have any of the following symptoms, stop taking isotretinoin and call or go to the nearest emergency room:.
Isotretinoin may cause blood sugar problems, including diabetes. Call your doctor if you have any of the following symptoms:. Another rare, serious side effect is a decrease in blood cell levels. Low levels of red blood cells can cause problems such as anemia. Low levels of white blood cells raise your risk of infections. Rarely, isotretinoin can cause serious mental health problems. These include depression, psychosis losing touch with reality , and suicidal thoughts or actions.
Taking isotretinoin during pregnancy carries an extremely high risk of severe birth defects. This is true if the drug is used in any amount and even for short periods of time. If you become pregnant during treatment with isotretinoin, stop taking the drug right away. A gynecologist can then give you further evaluation and counseling. Because of the risks it carries for pregnancies, isotretinoin can be prescribed only under a special restricted distribution program called iPLEDGE.
This program is approved by the Food and Drug Administration. Both males and females who take isotretinoin need to discuss this program with their doctor. Doctors who prescribe isotretinoin and pharmacies that dispense isotretinoin must be registered and activated with the iPLEDGE Program. The second pregnancy test must be done in a lab specified by your doctor. The program also requires females to choose and agree to use two forms of effective birth control at the same time.
This precaution goes along with the third requirement. That is, you must agree not to become pregnant while using isotretinoin and for one month before or after treatment. At least one of the birth control methods must be a primary form of birth control. You must have 2 negative pregnancy tests before you start taking isotretinoin, before each prescription is refilled, right after you take your last dose of isotretinoin, and again 30 days later.
You must agree in writing to use two specific forms of birth control beginning 30 days before you start taking isotretinoin and ending 30 days after your last dose. Both a primary and a secondary form of birth control must be used together. Stop using isotretinoin and call your doctor at once if you have unprotected sex, if you quit using birth control, if your period is late, or if you think you might be pregnant.
Not having sexual intercourse abstinence is the most effective method of preventing pregnancy. Get emergency medical help if you have signs of an allergic reaction hives, difficult breathing, swelling in your face or throat or a severe skin reaction fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. Do not take a vitamin or mineral supplement that contains vitamin A, unless your doctor tells you to. Do not donate blood while taking isotretinoin and for at least 30 days after you stop taking it.
Donated blood that is later given to a pregnant woman could lead to birth defects in her baby if the blood contains any level of isotretinoin. While you are taking isotretinoin and for at least 6 months after your last dose: Do not use wax hair removers or have dermabrasion or laser skin treatments.
Scarring may result. Isotretinoin could make you sunburn more easily. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen SPF 30 or higher when you are outdoors. Avoid driving or hazardous activity until you know how this medicine will affect you. Isotretinoin may impair your vision, especially at night. Use Isotretinoin Accutane exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Follow all directions on your prescription label and read all medication guides or instruction sheets.
Use the medicine exactly as directed. Each prescription of isotretinoin must be filled within 7 days of the date it was written by your doctor. You will receive no more than a day supply of isotretinoin at one time.
Always take isotretinoin with a full glass of water. Do not chew or suck on the capsule. Swallow it whole. Use this medicine for the full prescribed length of time. Your acne may seem to get worse at first, but should then begin to improve. Never share this medicine with another person, even if they have the same symptoms you have.
Skip the missed dose and use your next dose at the regular time. Do not use two doses at one time.
Back to Isotretinoin capsules Roaccutane. Isotretinoin capsules are only for severe acnesuch as acne with deep or multiple pus-filled spots, nodules or cysts that may affect the back, chest and limbs, as well as the face, and acne where there is a risk of permanent scarring. It's not clear exactly how they work, but isotretinoin capsules seem to help severe acne by stopping the sebaceous glands found near the surface of your skin from producing too much sebum the oily substance made naturally by your skin.
This means that blocked pores are less likely. Having less sebum also helps to reduce bacteria in your pores. Isotretinoin has an anti-inflammatory effect, helping to relieve redness and soreness.
Your acne may get worse when you first start treatment with isotretinoin capsules, but it will then normally start to improve after 7 to 10 days. There are various other medicines that your doctor might try before you are referred to a specialist.
For mild acne, there are a range of medicines that can be applied to your skin. These include other retinoid creams and gels or benzoyl peroxide cream and gel.
If these do not work then your doctor may prescribe a treatment that has an antibiotic and a retinoid or benzoyl peroxide. They might also choose another gel called azelaic acid. For some women, using a combined oral contraceptive may help.
For more severe acne, your doctor may try antibiotic tablets with a gel or cream before you are referred to a specialist, or while you are waiting for an appointment with a specialist.
Isotretinoin capsules are usually only prescribed by a specialist to people with severe acne whose acne does not improve with other treatments. Other options for people with severe acne include treatment that use lasers or lamps to provide light therapy photodynamic therapyand steroids given by mouth or injected into the lesions.
Isotretinoin used to also come as a gel to be applied to the skin, known by the brand names Isotrex and Isotrexin. These medicines are no longer available in the UK.
However, there are other medicines to be applied to the skin gels or creams that contain a retinoid, such as adapalene or tretinoin. These work in a similar way to isotretinoin gel. Ask your doctor or a pharmacist for advice about suitable alternatives and the best treatment for your condition.
Do not donate blood while taking isotretinoin capsules and for at least 1 month after stopping. If your blood is given to a pregnant woman, it may harm her baby. Isotretinoin capsules can make you feel sleepy and dizzy and affect your vision. In particular isotretinoin can affect your vision at night, which can happen suddenly. If this happens to you, do not drive, cycle, or use machinery or tools until these effects wear off.
It's an offence to drive a car if your ability to drive safely is affected. It's your responsibility to decide if it's safe to drive. If you're in any doubt, do not drive. Talk to your doctor or pharmacist if you're unsure whether it's safe for you to drive while taking isotretinoin.
UK has more information on the law on drugs and driving. It's best not to drink alcohol while taking isotretinoin capsules, or at least keep the amount you drink to a minimum.
This is because there's a risk of damage to your liver and that your cholesterol levels will increase. Apart from stopping or limiting alcohol, you can eat and drink normally while taking isotretinoin capsules. These lifestyle changes may help with your acne :.
Page last reviewed: 25 February Next review due: 25 February Common questions about isotretinoin capsules. How do isotretinoin capsules work? Isotretinoin is a retinoid medicine that is related to vitamin A. It can take 2 to 3 months for many of these treatments to work. These lifestyle changes may help with your acne : try not to wash affected areas of skin more than twice a day — too much washing can irritate your skin and make spots worse wash spotty skin with a mild soap or cleanser and lukewarm water — very hot or cold water can make acne worse never "clean out" blackheads or squeeze spots — this can make them worse and cause permanent scars do not use too much make-up or cosmetics — use water-based products described as non-comedogenic this means the product is less likely to block the pores in your skin remove make-up before going to bed use a fragrance-free moisturiser if dry skin is a problem shower as soon as possible after exercising, as sweat can irritate acne wash your hair regularly, and try to stop letting your hair fall across your face use a high protection factor SPF 15 or above sunscreen if the treatments you are using make your skin more sensitive to sunlight.
Here are some tips and instructions to help you get through your treatment. General Tips: Do not take any other medications with your isotretinoin. I cleared it with my derm and he told me no cold medicine will interfere or is unsafe to mix with accutane. I had to take some antibiotics. Do not take any extra medication that may interact with Accutane. This includes multivitamins. Please notify other physicians that you are taking Accutane, so. localhost › comments › ooqxi3 › can_y. Answer: Stop Accutane because of a cold? It's best not to go off the medication UNLESS you are put on some type of antibiotic for your throat. This medicine may cause serious allergic reactions, including anaphylaxis, which can be life-threatening and requires immediate medical attention. Contact lenses: This medication may cause dry eyes. Isotretinoin capsules are usually only prescribed by a specialist to people with severe acne whose acne does not improve with other treatments. Share this article.Isotretinoin is a vitamin A derivative that belongs to the class of medications called retinoids. Retinoids are typically used to treat skin problems. Isotretinoin is used to treat severe types of acne, such as nodular or inflammatory acne, where other medications with less potential for severe side effects have failed to help. It may also be used to treat acne conglobata and recalcitrant acne. Isotretinoin helps to reduce sebum production, which is often associated with bacteria that contributes to acne.
In many cases, it can produce remission of the acne condition. Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor.
Do not stop taking this medication without consulting your doctor. Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it. Record your current acne treatment and concerns to help your doctor find the best management strategies.
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The usual starting daily dose is 0. Based on body weight, severity of acne, and your response to the medication, your doctor will then adjust your dose. Isotretinoin should be taken as a single dose or in 2 divided doses during the day. Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
Your acne may get worse temporarily, before it gets better. Your doctor will adjust your daily dose after the initial treatment depending on your response to the medication. Food increases the amount of medication available to the body. It also helps to reduce upset stomach. For these reasons, isotretinoin medication should be taken with food.
The first signs of healing usually occur after 2 to 3 weeks of treatment, however, it may take 1 or 2 months before you see beneficial effects. The complete course of treatment usually lasts 12 to 16 weeks.
Most people with severe acne notice a marked improvement after 1 or 2 courses of treatment. You may continue to see even more improvement in your acne condition for several months after you have stopped taking the medication. If any of your side effects do not clear up in a few weeks after you stop taking your medication, speak to your doctor. Be sure to read the patient information that comes with each package of medication. It is important that this medication be taken exactly as prescribed by your doctor.
If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice. Store this medication at room temperature, in the original package, protect it from light and moisture, and keep it out of the reach of children.
Do not dispose of medications in wastewater e. Ask your pharmacist how to dispose of medications that are no longer needed or have expired. Isotretinoin should not be taken by women who may become pregnant unless all of the following conditions apply:.
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.
Many of these side effects can be managed, and some may go away on their own over time. Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects. Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.
Stop taking the medication and seek immediate medical attention if any of the following occur:. Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.
Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication. Behaviour changes and suicidal thoughts: Some people taking this medication have experienced depression, including thoughts of suicide.
If you experience any behaviour change or symptoms such as sad mood, hopelessness, feelings of guilt, loss of pleasure or interest in activities, changes in sleep pattern, irritability, or restlessness while taking this medication, contact your doctor immediately.
If you are at risk for developing depression or have a history of depression, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Family members or caregivers of people who are taking this medication should contact the person's doctor immediately if they notice unusual behaviour changes. Birth control: Isotretinoin causes birth defects in a large percentage of babies born to women who take this medication during pregnancy. Isotretinoin interacts with hormonal birth control i.
Two reliable forms of birth control should be used at the same time during treatment unless abstinence is the chosen method. Birth control must be used for at least one month before starting isotretinoin, during treatment with this medication and for at least one month after stopping the isotretinoin. Blood donation: You should not give blood during treatment with isotretinoin and for one month after stopping treatment in case the blood is given to a pregnant woman.
Bones and joints: Isotretinoin may cause some minor bone changes. Talk to your doctor if you notice aches or pains in the bones or joints, or have difficulty moving. Your doctor may monitor you for bone changes while you are taking this medication. Cholesterol: Isotretinoin can cause increases in cholesterol and other lipids in the blood.
If you are already at an increased risk of developing high cholesterol, for example if you have a family history of high cholesterol, diabetes, are overweight, or have an increased alcohol intake, you are more likely to experience this.
If you are at any increased risk of developing increased blood lipids, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed. Contact lenses: This medication may cause dry eyes. If you use contact lenses you may find them uncomfortable to wear.
You can help manage dry eyes by using a lubricating eye ointment or replacement tears. Diabetes: Isotretinoin may cause a loss of control of blood sugar levels for people with diabetes. If you have diabetes, or anyone in your family has diabetes, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
You may need to check your blood glucose levels more often. Inflammatory bowel disease: This medication may cause irritation in the digestive system. If you experience stomach pain, rectal bleeding or diarrhea, contact your doctor immediately.
Liver disease: Several cases of hepatitis inflammation of the liver have been reported that are considered to be possibly or probably related to isotretinoin therapy. If you experience symptoms of liver problems such as fatigue, feeling unwell, loss of appetite, nausea, yellowing of the skin or whites of the eyes, dark urine, pale stools, abdominal pain or swelling, and itchy skin, contact your doctor immediately. Muscle effects: There have been reports of muscle damage associated with use of isotretinoin, especially after strenuous physical activity.
Report any unexplained muscle pain, tenderness, weakness or cramps, or any brown or discoloured urine to your doctor immediately, particularly if you are also experiencing malaise a general feeling of being unwell or fever.
Neurologic: Isotretinoin has been linked to causing intracranial hypertension, also known as pseudotumor cerebri. Early symptoms of this condition include headache, nausea, vomiting, and visual disturbances.
If you have these symptoms call your doctor immediately. Night vision: Decreased night vision has been reported during isotretinoin therapy.
Because some patients experience sudden onset of vision problems, use caution when driving or operating any vehicle at night. Report any vision changes to your doctor. Pancreatitis: Isotretinoin can cause the pancreas to become inflamed. If you have a history of pancreatitis, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Report signs of pancreatitis such as abdominal pain on the upper left side, back pain, nausea, fever, chills, rapid heartbeat, or swollen abdomen to your doctor immediately. If you have a history of pancreatitis, gallstones, alcoholism, or high triglycerides, you may be more at risk of experiencing this.
Skin care: Isotretinoin causes irritated, dry skin and lips. Ask your doctor or pharmacist for appropriate moisturizers and lip balms to use to prevent severe dryness.
While you are taking isotretinoin, avoid exfoliators, waxing and dermabrasion, or laser procedures. Skin rash: Isotretinoin may cause skin rash or itchiness. Rarely, people taking isotretinoin experience a severe skin reaction that can be life threatening. If you experience a rash that gets worse, or develops into blisters, sores on the lips or eyes, or covers a large area of the body, contact your doctor immediately. Sun sensitivity: Isotretinoin may make you more likely to burn in the sun.
Use appropriate measures to prevent excessive exposure to the sun.
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