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Isotretinoin: MedlinePlus Drug Information |
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Isotretinoin (Accutane).
Keep isotretinoin away from children. You may not give blood while you are taking this medicine or for at least one month after you stop taking it. Tell your doctor if you or anyone in your family has diabetes, liver disease, heart disease or depression. You should also tell your doctor if you are allergic to any medicines, especially parabens which are in the isotretinoin capsules.
Be sure to tell your doctor if you are taking any other medicines, even over-the-counter medicines. Isotretinoin is like vitamin A, so you should not take vitamin A pills or multivitamins with vitamin A while you are taking isotretinoin. Your acne may get worse when you start using isotretinoin. This usually just lasts for a little while.
You can tell your doctor if this happens to you because you might need to use other medicines along with the isotretinoin in this stage. The dosage of isotretinoin is different for each person.
During your treatment, your doctor may change your dosage. Be sure to take isotretinoin just the way your doctor tells you. If you miss one dose, don't take extra the next time.
Be sure you keep all of your appointments with your doctor because your doctor needs to check on you often. Your doctor may check your liver tests and cholesterol levels. During treatment you may have some of the following side effects. Between and , more than 2, women became pregnant while taking isotretinoin, almost all ending in abortion or miscarriage. The U. Food and Drug Administration introduced the iPledge program in , requiring prescribers to register, and female patients of childbearing age to qualify by pledging to use two forms of birth control and take doctor-administered pregnancy tests for two consecutive months.
With two negative pregnancy tests and a completed online comprehension test, the patient will be authorized to pick up her prescription, and has to return to the doctor for pregnancy tests every 30 days while taking the medication. Then the women reviewed an information sheet about the contraceptive methods that the researchers had specially designed, and retook the effectiveness survey.
More than half of the women surveyed said they had seen a physician for acne problems in the past year, and 11 women said they had ever used isotretinoin. Straight Healthcare. Other lipid effects are typically transient and insignificant. Results from studies that have evaluated the effect have been conflicting.
Repeat scans conducted within 2 to 3 months after the post-treatment scan showed no recovery of BMD. There are currently 4 generic versions of isotretinoin available Amnesteem, Myorisan, Claravis, Zenatane. Absorica LD is micronized isotretinoin, and it is not equivalent to Absorica on a mg-to-mg basis. Initial visit Step 1 - Give patient isotretinoin educational kit male or female who cannot become pregnant and obtain the unique patient ID number from the kit Step 2 - Counsel patient on the side effects of isotretinoin.
Anyone who has taken an overdose of isotretinoin should know about the risk of birth defects caused by isotretinoin and should not donate blood for 1 month after the overdose. Pregnant woman should talk to their doctors about the risks of continuing the pregnancy after the overdose. Women who can become pregnant should use two forms of birth control for 1 month after the overdose. Men whose partners are or may become pregnant should use condoms or avoid sexual contact with that partner for 1 month after the overdose because isotretinoin may be present in the semen.
Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to isotretinoin.
It is important for you to keep a written list of all of the prescription and nonprescription over-the-counter medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Generic alternatives may be available. Isotretinoin pronounced as eye soe tret' i noyn. Why is this medication prescribed? How should this medicine be used? Other uses for this medicine What special precautions should I follow?
What special dietary instructions should I follow? What should I do if I forget a dose? What side effects can this medication cause? What should I know about storage and disposal of this medication? Brand names. For all patients: Isotretinoin must not be taken by patients who are pregnant or who may become pregnant. Do not donate blood while you are taking isotretinoin and for 1 month after your treatment. Talk to your doctor about the risks of taking isotretinoin. For female patients: If you can become pregnant, you will need to meet certain requirements during your treatment with isotretinoin.
For male patients: A very small amount of isotretinoin will probably be present in your semen when you take prescribed doses of this medication.
Other uses for this medicine. What special precautions should I follow? Before taking isotretinoin, tell your doctor and pharmacist if you are allergic to isotretinoin, vitamin A, any other medications, or any of the ingredients in isotretinoin capsules. Ask your pharmacist or check the Medication Guide for a list of the inactive ingredients. Be sure to mention medications for seizures such as phenytoin Dilantin ; medications for mental illness; oral steroids such as dexamethasone Decadron, Dexone , methylprednisolone Medrol , and prednisone; tetracycline antibiotics such as demeclocycline Declomycin , doxycycline Monodox, Vibramycin, others , minocycline Minocin, Vectrin , oxytetracycline Terramycin , and tetracycline Sumycin, Tetrex, others ; and vitamin A supplements.
Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Also tell your doctor if you are overweight or if you drink or have ever drunk large amounts of alcohol.
Please note: This information was current at the time of publication but now may be out of date. This handout provides a general overview and may not apply to everyone.
For regularly updated information on a variety of health topics, please visit familydoctor. Isotretinoin brand name: Accutane is a medicine for very bad acne that did not get better after you tried other medicines. It is important for you to take isotretinoin the right way. You should know about the side effects of isotretinoin. Talk to your doctor if you have any questions about this medicine or if you have side effects when you take it.
You should take isotretinoin with food. You don't have to keep the medicine in the refrigerator, but keep it out of sunlight. Try not to keep it in a place that is very warm. Isotretinoin has been prescribed just for you. Don't share it with other people.
Keep isotretinoin away from children. You may not give blood while you are taking this medicine or for at least one month after you stop taking it. Tell your doctor if you or anyone in your family has diabetes, liver disease, heart disease or depression.
You should also tell your doctor if you are allergic to any medicines, especially parabens which are in the isotretinoin capsules. Be sure to tell your doctor if you are taking any other medicines, even over-the-counter medicines. Isotretinoin is like vitamin A, so you should not take vitamin A pills or multivitamins with vitamin A while you are taking isotretinoin.
Your acne may get worse when you start using isotretinoin. This usually just lasts for a little while. You can tell your doctor if this happens to you because you might need to use other medicines along with the isotretinoin in this stage.
The dosage of isotretinoin is different for each person. During your treatment, your doctor may change your dosage. Be sure to take isotretinoin just the way your doctor tells you. If you miss one dose, don't take extra the next time. Be sure you keep all of your appointments with your doctor because your doctor needs to check on you often. Your doctor may check your liver tests and cholesterol levels. During treatment you may have some of the following side effects.
These side effects usually go away when you stop taking isotretinoin:. Decreased night vision. If you have any vision problems, you should stop taking isotretinoin and talk to your doctor right away. A few people have even more serious side effects. If they aren't treated, the problem could last forever. If you have any of the side effects listed below, stop taking isotretinoin and check with your doctor right away:.
Your skin might go on getting better even after you stop taking isotretinoin. Most of the side effects of isotretinoin go away in a few days or weeks after you stop taking isotretinoin. If your side effects last more than a few weeks after you stop taking isotretinoin, talk to your doctor.
Some patients have to take isotretinoin more than one time. If you need to take isotretinoin again, you can start taking it again 8 to 10 weeks after your first treatment is over. Do not give blood for at least one month after you stop taking isotretinoin. You must not take isotretinoin if you are pregnant or if there is any chance you might get pregnant while taking this medicine!
Isotretinoin causes severe birth defects, including malformation of the head and face, mental retardation and severe internal defects of the brain, heart, glands and nervous system. It can also cause miscarriage, premature birth and death of the fetus. You must use two forms of birth control at the same time for at least one month before you start taking isotretinoin and for all the time you are taking this medicine.
Keep using two kinds of birth control for one month after you stop taking isotretinoin. If you are using Depo-Provera as your form of birth control, you may not need to use two forms of birth control.
Check this with your doctor. Your doctor will make sure you are not pregnant before starting isotretinoin and check again every month while you are taking it. You will be asked to read and sign a consent form to show that you understand the dangers of birth defects and agree to use birth control.
If your period is late, stop taking isotretinoin and call your doctor right away. If you get pregnant while you are taking isotretinoin, talk with your doctor about going on with the pregnancy. This content is owned by the AAFP. A person viewing it online may make one printout of the material and may use that printout only for his or her personal, non-commercial reference. This material may not otherwise be downloaded, copied, printed, stored, transmitted or reproduced in any medium, whether now known or later invented, except as authorized in writing by the AAFP.
What is isotretinoin? General Information. Before Treatment Starts. During Your Treatment. Dry skin and lips your doctor can tell you which lotions or creams to use Fragile skin easily injureditching or rash Increased sensitivity to the sun easily sunburned Peeling skin on your palms and soles Thinning hair Dry, red eyes you may find that you can't wear your contact lenses during treatment Nosebleeds Bleeding gums Pain in your muscles Decreased night vision.
Headaches, nausea, vomiting or blurred vision Depression or changes in your mood Severe stomach pain, diarrhea or bleeding from your rectum Very dry eyes A yellow color in your skin or eyes, and dark yellow urine.
After You Stop Taking Isotretinoin. Attention, Girls and Women:. Continue Reading. More in AFP. All Rights Reserved.
Isotretinoin: learn about side effects, dosage, special precautions, and more on MedlinePlus. The Slone Accutane Survey has reported similar findings with an annual rate of per women-years [3]. Isotretinoin is an effective drug for acne, and. The Slone Accutane Survey has reported similar findings with an annual rate of per women-years [3]. Isotretinoin is an effective drug for acne, and. Isotretinoin (brand name: Accutane) is a medicine for very bad acne that If you are using Depo-Provera as your form of birth control. Contraceptive injection. However, it is well known that Roaccutane can cause Lasts for 12 weeks (Depo-Provera). You will need to see your doctor every month during your treatment to talk about your condition and the side effects you are experiencing. Keep all appointments with your doctor and the laboratory. Information about your health and your baby's health will be used to help doctors learn more about the effects of isotretinoin on unborn babies. After You Stop Taking Isotretinoin. A program called iPLEDGE has been set up to make sure that pregnant women do not take isotretinoin and that women do not become pregnant while taking isotretinoin.Straight Healthcare. Other lipid effects are typically transient and insignificant. Results from studies that have evaluated the effect have been conflicting. Repeat scans conducted within 2 to 3 months after the post-treatment scan showed no recovery of BMD. There are currently 4 generic versions of isotretinoin available Amnesteem, Myorisan, Claravis, Zenatane.
Absorica LD is micronized isotretinoin, and it is not equivalent to Absorica on a mg-to-mg basis. Initial visit Step 1 - Give patient isotretinoin educational kit male or female who cannot become pregnant and obtain the unique patient ID number from the kit Step 2 - Counsel patient on the side effects of isotretinoin. Counsel patient not to share the drug or donate blood. Step 3 - Have patient sign the informed consent in the educational kit.
Put signed consent in patient's medical record and give a copy to the patient. You will need the ID number from the kit. Step 5 - Prescribe one month of isotretinoin. Prescription can be filled for 30 days only. Prescription must be filled at a registered pharmacy. Monthly follow-up visits Step 1 - Counsel patient not to share the drug or donate blood Step 2 - Go online and confirm that you have counseled the patient Step 3 - Prescribe one month of isotretinoin. During the last month of therapy, confirm that patient knows not to donate blood for 30 days after their last dose.
Initial visit Step 1 - Give patient isotretinoin educational kit female who can become pregnant and obtain the unique patient ID number from the kit Step 2 - Counsel patient on the side effects of isotretinoin. If the provider wishes to refer a patient for counseling, there is a section in the educational kit that explains how to do this. Step 3 - Have patient sign the two informed consents in the educational kit. Step 5 - Perform urine or serum pregnancy test CLIA-certified not necessary Step 6 - Confirm that patient is on 2 forms of approved contraception see contraception below.
Abstinence is another option and is discussed below see abstinence. Step 7 - Have patient follow-up in about 30 days First follow-up visit Step 1 - Confirm that patient has used 2 acceptable forms of birth control for last 30 days see contraception below Step 2 - Order second pregnancy test urine or serum, must be CLIA-certified.
See second pregnancy test above for details on test timing. Prescription can be filled for 7 days only day 1 is the day pregnancy test is collected. Step 3 - Counsel patient on using 2 forms of birth control and not to share the drug or donate blood.
Patient should have follow-up visit at the end of therapy and 30 days after her last dose. Pregnancy tests and reporting are required at these visits. Counsel patient not to donate blood and to use contraception for 30 days after her last dose.
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